6-Iodo-4-Hydroxyquinazoline CAS 16064-08-7 Purity >98.5% (HPLC) Factory

Short Description:

Chemical Name: 6-Iodo-4-Hydroxyquinazoline

CAS: 16064-08-7

Purity: >98.5% (HPLC)

Appearance: Pale Yellow to Brown Crystal Powder

Intermediate of API (CAS: 388082-78-8)

Contact: Dr. Alvin Huang

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E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Lapatinib Intermediates:

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Chemical Properties:

Chemical Name	6-Iodo-4-Hydroxyquinazoline
Synonyms	6-Iodoquinazolin-4-one; 6-Iodo-4-Quinazolinone; 6-Iodoquinazolin-4(3H)-one; 6-Iodo-4(1H)-Quinazolinone; 6-Iodo-4-Quinazolinol
CAS Number	16064-08-7
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C8H5IN2O
Molecular Weight	272.04
Melting Point	271℃ (lit.)
Density	2.11±0.10 g/cm3
COA & MSDS	Available
Origin	Shanghai, China
Brand	Ruifu Chemical

Specifications:

Item	Specifications	Specifications
Appearance	Pale Yellow to Brown Crystal	Complies
Identification	H-NMR, MS	Complies
Loss on Drying	<1.00%	0.45%
Residue on Ignition	<0.10%	<0.10%
Purity / Analysis Method	>98.5% (HPLC)	98.79% (HPLC)
1 H NMR Spectrum	Consistent With Structure	Complies
Test Standard	Enterprise Standard
Usage	Intermediate of API (CAS: 388082-78-8)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

FAQ:

16064-08-7 - Risk and Safety:

Risk Codes
36 - Irritating to the eyes
Safety Description
26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

16064-08-7 - Application:

6-Iodo-4-Hydroxyquinazoline (CAS: 16064-08-7) is an intermediate in the synthesis of API (CAS: 388082-78-8). (CAS: 388082-78-8) is available in 250-mg tablets for oral administrationand is used in combination with Cabecitabine in thetreatment of breast cancer for those patients that over expressthe type 2 EGF-R and who have previously receivedtaxane, anthracycline, and trastuzumab therapy. The type 2EGF-R is one subtype of this receptor and is also known asHER2 or ErbB-2. The agent is a receptor TK inhibitor targetingthe ErbB-1 and ErbB-2 subtypes.